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Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone

Crossref DOI link: https://doi.org/10.1186/s12891-018-2221-5

Published Online: 2018-08-16

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hoshino, Takashi

Tsuji, Kunikazu https://orcid.org/0000-0002-1013-8359
Onuma, Hiroaki

Udo, Mio

Ueki, Hiroko

Akiyama, Masako

Abula, Kahaer

Katagiri, Hiroki

Miyatake, Kazumasa

Watanabe, Toshihumi

Sekiya, Ichiro

Koga, Hideyuki

Muneta, Takeshi
Funding

Funding for this research was provided by:

Japan Society for the Promotion of Science (25293317)

Japan Society for the Promotion of Science (25460719)

Japan Society for the Promotion of Science (26462287)

Japan Agency for Medical Research and Development (122011A182)

Japan Agency for Medical Research and Development (122012A109)
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Article History

Received: 24 April 2018

Accepted: 3 August 2018

First Online: 16 August 2018

Ethics approval

: The Institutional Animal Care and Use Committee of the Tokyo Medical and Dental University approved this study (approval no. A2017-259A). All animal experiments were conducted per institutional guidelines.

: Not applicable.

: The authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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