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Authors
Dyer, Brett P. https://orcid.org/0000-0001-8039-7631
Burton, Claire https://orcid.org/0000-0003-4688-3075
Rathod-Mistry, Trishna https://orcid.org/0000-0002-6369-4746
Blagojevic-Bucknall, Miliça https://orcid.org/0000-0001-7230-7771
van der Windt, Danielle A. https://orcid.org/0000-0002-7248-6703
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Funding
Funding for this research was provided by:
Versus Arthritis (21899)
National Institute for Health and Care Research
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Article History
Received: 21 August 2024
Accepted: 17 April 2025
First Online: 14 May 2025
Declarations
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: The authors confirm that this study adhered to the Declaration of Helsinki. The CPRD has been granted generic ethics approval for observational studies that make use of only anonymised data and linked anonymised NHS health-care data (Multiple Research Ethics Committee ref. 05/MRE04/87). All CPRD studies require scientific approval from the MHRA Independent Scientific Advisory Committee (ISAC). The ISAC was established by the Secretary of State for Health in February 2006 to review the scientific merit of proposals for research using data from the CPRD as well as the Yellow Card Scheme database. This study’s protocol was approved and is registered as #19_219R. All the participants provided their informed consent and each individual GP practice participating in CPRD’s collection of their primary care data can choose to revoke their consent for data collection at any point. CPRD respects all patient opt-outs. Patients who have registered an opt-out will not be extracted for CPRD research or for data linkage. Researchers using the data must adhere to robust terms and conditions governing how the anonymized data is used.
: Not applicable.
: The authors declare no competing interests.
