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TLR2 and IRF8 are the biomarkers associated with hypoxia in steroid-induced osteonecrosis of the femoral head via bioinformatics analysis and experimental validation

Crossref DOI link: https://doi.org/10.1186/s12891-025-09132-7

Published Online: 2025-09-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Jing

Wang, Junfang

Guo, Jing

Wei, Biaofang
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Text and Data Mining valid from 2025-09-02

Version of Record valid from 2025-09-02
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Article History

Received: 6 February 2024

Accepted: 19 August 2025

First Online: 2 September 2025

Declarations

:

: The study was conducted in accordance with the principles of the Declaration of Helsinki, and approved by the Ethics Committee of Linyi People’s Hospital (YX200342). All patients signed a required informed consent to undergo the procedure.

: Not applicable.

: The authors declare no competing interests.

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