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Effectiveness of preoperative intravenous tranexamic acid on reduction of perioperative blood loss in open intramedullary nail fixation of femoral shaft fractures in a tertiary hospital, Uganda: a prospective cohort study

Crossref DOI link: https://doi.org/10.1186/s12891-026-09793-y

Published Online: 2026-04-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kabazzi, Paul Kaweesa

Sekimpi, Patrick

Kironde, Edward

Nsubuga, Yakobo https://orcid.org/0000-0001-5592-732X
Mirembe, Esther
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Text and Data Mining valid from 2026-04-14

Version of Record valid from 2026-05-22
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Article History

Received: 8 December 2025

Accepted: 1 April 2026

First Online: 14 April 2026

Declarations

:

: Ethical approval for this study was obtained from the Makerere University School of Medicine Research and Ethics Committee (SOMREC), reference number 2018-168. Administrative permission to conduct the study was also granted by the Department of Orthopaedics at Mulago National Referral Hospital.All participants provided written informed consent prior to enrollment in the study. The study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki.

: Not applicable.

: The authors declare no competing interests.

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