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Article History

Received: 15 October 2024

Accepted: 2 May 2025

First Online: 10 May 2025

Declarations

:

: All data were collected from patients who gave their informed consent themselves or through legal representatives. This study is a retrospective analysis utilizing existing clinical data. The research protocol has been approved by Ethics Committee in Clinical Research (ECCR)of the First Affiliated Hospital of Wenzhou Medical University: (No. KY2024-R233), and the conduct of the study adheres to the Declaration of Helsinki and relevant ethical standards. Due to the nature of the study, patient data involved have been de-identified, and thus the Ethics Committee has waived the requirement for patient informed consent.

: This study was approved by the Ethics Committee in Clinical Research (ECCR) of the First Affiliated Hospital of Wenzhou Medical University (Approval No. KY2024-R233). The study was conducted in accordance with the Declaration of Helsinki and its later amendments or comparable ethical standards. For this retrospective analysis, which involved the use of existing clinical data, the Ethics Committee waived the requirement for patient informed consent due to the de-identified nature of the data. However, it is important to note that all patients at our hospital provide general consent for the use of their medical records for teaching and research purposes as part of the informed consent process prior to receiving oral treatment.

: Not applicable.

: The authors declare no competing interests.