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Minimally invasive pouch technique with leukocyte platelet rich fibrin compared to non-invasive hyaluronic acid injection in reconstruction of interdental papilla in esthetic zone: a randomized clinical trial

Crossref DOI link: https://doi.org/10.1186/s12903-025-06127-7

Published Online: 2025-07-26

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Alleithy, Aya

Abuel-Ela, Hala

Sarhan, Susan
Funding

Funding for this research was provided by:

Ain Shams University
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Text and Data Mining valid from 2025-07-26

Version of Record valid from 2025-07-26
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Article History

Received: 13 October 2024

Accepted: 7 May 2025

First Online: 26 July 2025

Declarations

:

: The trial is applicable for both human and/or animal studies. Approval was obtained from the Research Ethics Committee, Faculty of Dentistry, Ain Shams University with approval number (ID: IM012112). Individual patients’ data and results have been kept confidential by a filing system with passwords to protect them from being preached. Patient’s names were not shown in the analyzed data; instead, they were encoded by a coding system known by the main investigator only. The study was conducted by the Declaration of Helsinki on Ethical Principles for Medical Research Involving Human Subjects.The registry Identifier for this study is (NCT05953896). All patients gave written consent to participate by signing the informed consent form before participation in the study.

: Not applicable.

: The authors declare no competing interests.

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