Fan, Yadan
Lin, Zhikai
Cheng, Lan
Ge, Linhua
Funding for this research was provided by:
National Natural Science Foundation of China (81991503)
Shanghai Municipal Key Clinical Specialty (Shanghai Municipal Key Clinical Specialty)
Shanghai Clinical Research Center for Oral Diseases (19MC1910600)
Innovative Research Team of High-level Local Universities of Shanghai Jiao Tong University School of Medicine 2018 (SSMU- ZDCX20180900)
Article History
Received: 24 November 2024
Accepted: 23 June 2025
First Online: 2 July 2025
Declarations
:
: Our research was granted approval by the institutional ethical committee of the Ninth People’s Hospital Affiliated to Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine (Approval number: SH9H-2019-T208-1), and the study was registered with the clinical trial registry, China (ChiCTR2000029251, 2020-01-20). Informed consent was well understood and signed by all participants. All methods were carried out in accordance with relevant standard guidelines and regulations.
: Informed written consent was taken from trial participants before history taking, examination and trial procedure at baseline as well as at each follow-up. All methods were carried out in accordance with relevant standard guidelines and regulations.
: The authors declare no competing interests.