Zhang, Jie
Jiang, Hong
Lao, Zhentao
Yang, Le
Hu, Yiming
Li, Wenbo
Xiao, Yudong
Liao, Guiqing
Deng, Wei
Liang, Yujie
Funding for this research was provided by:
National Natural Science Foundation of China (No.82072995)
Basic and Applied Basic Research Foundation of Guangdong Province (No.2022A1515010442)
Regional Joint Fund-Youth Foundation Project of Guangdong Province (No.2021A1515110255)
Article History
Received: 21 July 2025
Accepted: 12 November 2025
First Online: 9 December 2025
Declarations
:
: The trial is conducted in accordance with the Declaration of Helsinki. The participants in the study had been informed of all relevant details and the voluntary nature of the research study, including its purpose, procedures, anticipated risks, and benefits. And written informed consent was signed prior to beginning the study. Also, participants are informed that they can cease their participation in the study at any time without disclosing reasons for their cancellation and without negative consequences for their future medical care. The study protocol was approved by the institutional ethics committee and research review boards of the Hospital of Stomatology, Sun Yat-sen University, China (Grant Number: ERC- [2015]-29).
: Not applicable.
: Informed consent was obtained from all individual participants included in the study.
: The authors declare no competing interests.