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Article History

Received: 18 August 2025

Accepted: 8 December 2025

First Online: 12 December 2025

Declarations

:

: Following the definition of study objectives and methodology, ethical approval was granted by the Ethics Committee of the Jena University Hospital in accordance with the Declaration of Helsinki and the ICH-GCP (registration number: 2023-2928-Daten). To protect patient privacy, we strictly comply with data privacy and protection laws and regulations and have undergone strict anonymization of all patient data during the collection process. Due to the use of de-identified historical medical records in this study and the fact that the study protocol posed no additional risks to participants, the ethics committee waived informed consent.

: Not applicable.

: The authors declare no competing interests.