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Authors
Lee, Seung-Kyu
Lim, Kyeong-Ok
Yang, Keon-Il
You, Sang-Joun
Kang, Mi-Sun
Lee, Won-Pyo
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Funding
Funding for this research was provided by:
The Health Functional Food Development Support Program by the Ministry of Small and Medium Enterprises (SMEs) and Startups (No. RS-2022-00167206)
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Article History
Received: 9 December 2025
Accepted: 23 February 2026
First Online: 4 March 2026
Declarations
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: This study was conducted at Chosun University Dental Hospital and approved by the Institutional Review Board of Chosun University Dental Hospital (Approval No. CUDHIRB 2401 005). This clinical trial was registered at the Clinical Research Information Service (CRIS), Republic of Korea (KCT0009810). All procedures involving human participants were performed in accordance with the ethical standards of the institutional and national research committee, the Declaration of Helsinki, and local statutory requirements. Written informed consent was obtained from all participants prior to enrollment, and all participants provided consent for the publication of anonymized data.
: Not applicable.
: Mi-Sun Kang is an employee of Oraticx Inc. and served as the principal investigator for the government-funded project that supported this study. Her involvement in this research was limited to funding acquisition and the provision of study resources, and she had no role in participant recruitment, randomization, data collection, data analysis, data interpretation, or manuscript preparation. All other authors declare no competing interests.
