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Pharmacokinetics of five phthalides in volatile oil of Ligusticum sinense Oliv.cv. Chaxiong, and comparison study on physicochemistry and pharmacokinetics after being formulated into solid dispersion and inclusion compound

Crossref DOI link: https://doi.org/10.1186/s12906-021-03289-z

Published Online: 2021-04-22

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hu, Peng-yi

Zhong, Ying-huai

Feng, Jian-fang

Li, Dong-xun

Deng, Ping

Zhang, Wen-liu

Lei, Zhi-qiang

Liu, Xue-mei

Zhang, Guo-song
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81760714)

National Natural Science Foundation of China (81660667)

Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources Recycle (20171ACH-80003)

Jiangxi Provincial Academic and Technology Leader Funding Project (20182BCB22023)

Jiangxi Provincial Chinese Medicine First-Class Discipline Special Scientific Research Fund Project (JXSYLXK-ZHYAO051, JXSYLXK-ZHYAO091)
License Information

Text and Data Mining valid from 2021-04-22

Version of Record valid from 2021-04-22
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Article History

Received: 22 August 2020

Accepted: 29 March 2021

First Online: 22 April 2021

Declarations

:

: The studies were approved by the animal ethics committee of Jiangxi University of Traditional Chinese Medicine (jzllsc0137). All animals were maintained in accordance with the guidelines outlined by the Chinese legislation on the ethical use and care of laboratory animals. All efforts were made to minimize both animal suffering and the number of animals used to produce reliable data.

: Not applicable.

: The authors declare that they have no competing interests.

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