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Optimization of in vivo antimalarial efficacy of combinations of aqueous leaf extracts of Artemisia annua L., Vernonia amygdalina Del, and Microglossa pyrifolia (Lam.) Kuntze using factorial design

Crossref DOI link: https://doi.org/10.1186/s12906-024-04691-z

Published Online: 2024-11-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Angupale, Jimmy R.

Ajayi, Clement O.

Tusiimire, Jonans

Ngwuluka, Ndidi C.
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Text and Data Mining valid from 2024-11-13

Version of Record valid from 2024-11-13
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Article History

Received: 22 January 2024

Accepted: 29 October 2024

First Online: 13 November 2024

Declarations

:

: The research and animal experimental protocols used in this study were reviewed and approved at various levels at Mbarara University of Science and Technology (Uganda). The technical approvals were obtained at the department of pharmaceutical sciences and pharmacy, and Faculty Research Committee (FRC). The final research ethical approval/ permission for use of laboratory animals was obtained from Mbarara University of Science and Technology Research Ethical Committee (MUST-REC, MUST-2021–171). All the research assistants and technical staff who participated in conduct of the experiments received appropriate trainings in animal care and use, then on management of pain and distress in laboratory mice and rats. All the approved procedures in the protocol were performed and reported in accordance with Animal Research Reporting of In Vivo Experiments (ARRIVE) guidelines and regulations.

: The work does not contain any individual or personal data in form of images or videos that requires consent before publication.

: The authors declare no competing interests.

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