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Uncovering key anti-inflammatory constituents and mechanism of Wuwei Xiaodu Decoction by a combined strategy of phytochemistry, AIDD, network pharmacology, and in vitro and in vivo assay

Crossref DOI link: https://doi.org/10.1186/s12906-025-05072-w

Published Online: 2025-09-30

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Binghui

Zhou, Zhaoyin

Zhang, Yong

Zhu, Jing

Liu, Qiyuan

Ma, Jing

Gong, Zhangbin

Xu, Zhijian

Shen, Jingshan

Zhu, Weiliang

Chen, Jia
Funding

Funding for this research was provided by:

School of Medicine, Shanghai Jiao Tong University (QN-SCMC2024-1)
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Text and Data Mining valid from 2025-09-30

Version of Record valid from 2025-09-30
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Article History

Received: 18 April 2025

Accepted: 7 August 2025

First Online: 30 September 2025

Declarations

:

: The animal feeding and animal experiments strictly followed the experimental animal welfare policy. The Institutional Animal Care and Use Committee (IACUC) of Shanghai University of Traditional Chinese Medicine approved and reviewed the animal experiment on July 24, 2023 (Ethics No. PZSHUTCM2307240002).

: All authors have provided their consent for publication of the manuscript.

: The authors declare no competing interests.

: Not applicable.

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