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Authors
Liu, Dan
Kababji, Samer El
Mitsakakis, Nicholas
Pilgram, Lisa
Walters, Thomas D.
Clemons, Mark
Pond, Gregory R.
El-Hussuna, Alaa
Emam, Khaled El
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Article History
Received: 4 July 2025
Accepted: 28 October 2025
First Online: 28 November 2025
Declarations
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: This project was approved by the Research Ethics Board of the Children’s Hospital of Eastern Ontario Research Institute protocol 24/80x. The hot flashes data analysis was approved by the Ottawa Health Sciences Research Ethics Board protocols OHSN REB #20210727-01 H and OHSN REB #20210827-01 H. For the DCCG dataset, Danish Data Protection Agency (Datatilsynet) approval was obtained (RN-2018–94).Because the datasets used in this study were de-identified, obtaining participant consent was waived by the Research Ethics Board of the Children’s Hospital of Eastern Ontario Research Institute.This project adhered to the Declaration of Helsinki.
: Not applicable.
: KEE was the Scholar-in-Residence at the Office of the Information and Privacy Commissioner of Ontario when most of the work reported here was being conducted. KEE held shares in Aetion, which provided the sequential synthesis generative model software that was used in this study, when the study was conducted. Both of these have expired.
