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An integrated evaluation framework for synthetic clinical data in severely imbalanced settings: fidelity, privacy-risk profiling, and diagnostic utility

Crossref DOI link: https://doi.org/10.1186/s12911-026-03648-1

Published Online: 2026-06-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kim, Youngtae

Lee, Jungwoo

Koh, Sang Baek

Lee, Kyu Hee
Funding

Funding for this research was provided by:

Korea Evaluation Institute of Industrial Technology (RS-2025-13882968)

National Research Foundation of Korea (RS-2025-24683718)
License Information

Text and Data Mining valid from 2026-06-25

Accepted Manuscript valid from 2026-06-25
More Information

Article History

Received: 22 December 2025

Accepted: 17 June 2026

First Online: 25 June 2026

Declarations

:

: The study was reviewed and approved by the Institutional Review Board of Wonju Severance Christian Hospital, Wonju, Republic of Korea (IRB No. CR324352). All procedures involving human participants were performed in accordance with the Declaration of Helsinki and its later amendments. Written informed consent was obtained from all participants prior to enrollment.

: Not applicable.

: The authors declare no competing interests.

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