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Article History

Received: 28 October 2024

Accepted: 27 June 2025

First Online: 7 July 2025

Declarations

:

: This study The experiment has or participants have given informed consent and signed an informed consent form and approved by the Ethics Committee of Guangdong province people’s hospital (NO.KY2023-646), which operates in accordance with ethical principles such as the Declaration of Helsinki and the requirements of national laws and regulations: (1) All biomedical researches involving human beings need to be registered in the Medical Research Registration and Filing Information System (MRFIS) for record-keeping after ethical approvals have been granted. All biomedical research involving human beings must be registered in the “Medical Research Registration and Filing Information System” after ethical approval before launching. (2) In order to fully guarantee the rights and interests of the research subjects, if there are any changes in the research protocol, informed consent and recruitment materials, or if there are any serious adverse events (in human) or other unforeseen circumstances after the commencement of the trial, please report them to the Committee, which has the right to decide whether or not to terminate the trial. (3) For projects with a duration of more than one year, an annual progress report shall be submitted to the Ethics Committee for follow-up and review. (4) submit the research project completion report to the Ethics Committee for review.

: Not applicable.

: The authors declare no competing interests.