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Article History

Received: 20 March 2017

Accepted: 13 July 2018

First Online: 20 July 2018

Ethics approval and consent to participate

: This study is an observational study neither intervention nor taking human samples from patients. The study was approved by the local institutional review board (Comitato Etico Università “Federico II”, Naples, Italy – Protocol reference #1225/15). All patients provided their informed consent prior to data collection and analysis.

: Not applicable.

: MB received sponsorship for educational purposes, was paid for providing consultancy services, and took part in clinical trials sponsored by Shire, Pharming NV, CSL-Behring, and SOBI. No competing interests are recognizable for the other authors.

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