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Article History

Received: 3 September 2020

Accepted: 4 November 2020

First Online: 17 November 2020

Ethics approval and consent to participate

: The Medical research Ethics Committees United (MEC-U) in Nieuwegein, the Netherlands, has approved that the current study is not subject to the Medical Research Involving Human Subjects Act (reference number: W18.169). Therefore, approval will be obtained from the local medical ethics committees of all participating hospitals. At time of submission of this manuscript, ethical approval has been received from: the Executive Board of BovenIJ Ziekenhuis (reference: ECO-stroke), the Research Bureau of Noordwest Ziekenhuisgroep (reference number: L019–007), the Medical Ethics Committee of Ziekenhuis Amstelland (reference: ECO-stroke), the Medical Ethics Committee of Het Van Weel-Bethesda Ziekenhuis (reference: ECO-stroke), the Research Bureau of Tergooi (reference number: 19.24), the Research Bureau of Maasstad Ziekenhuis (L2019031), the Medical Ethics Review Committee of Zuyderland (reference: ECO-stroke), the Advisory Committee Medical Research of OLVG (reference number: WO 18.135) and the Local Review Committee of Gelre ziekenhuizen (reference: ECO-stroke). Written informed consent will be obtained from all participants.

: Not applicable.

: The authors declare that they have no competing interests.