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Article History

Received: 23 November 2017

Accepted: 27 March 2018

First Online: 29 May 2018

Ethics approval and consent to participate

: The Icona study was approved by ethical committees of all participating centers: Ancona, Bari, Bergamo, Bologna, Brescia, Busto Arsizio, Cagliari, Catania, Chieti, Ferrara, Firenze, Genova, Latina, Lecco, Macerata, Milano, Modena, Monza, Napoli, Padova, Palermo, Perugia, Pescara, Reggio Emilia, Roma, Rovigo, Sassari, Siena, Siracusa, Terni, Torino, Udine, Vicenza, and Viterbo. All subjects participating in the Icona study have signed an informed consent.

: The authors declare that they have no competing interests.

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