Updates are available Correction dated 2019-07-27

Article History

Received: 20 December 2018

Accepted: 25 April 2019

First Online: 4 June 2019

Change Date: 27 July 2019

Change Type: Correction

Change Details: Figure 3 in the original article [1] is incorrect; labels for secondary outcomes have been shifted and do not correspond to the numbers reported in the table (Additional file 8). The corrected version can be seen ahead. This figure should be used over the figure 3 seen in the original article. This error does not affect the results, interpretation, or conclusion.

Ethics approval and consent to participate

: This study obtained ethics approval from the Institutional Review Board of INSERM (registration No IRB00003888). The study was registered on ExternalRef removed with the following identifiers: NCT03094078 for preclinical studies, NCT03094104 for phase I/II non-randomized trials, and NCT03095586 for phase III/IV RCTs. All participants provided online consent.

: Not applicable

: IB is an academic editor at BMC Medicine. IO is employed by Medscape, which is part of WebMD. He is also the volunteer co-founder of Retraction Watch, which has been paid writing fees for journalism by Science magazine, STAT News, The Boston Globe, and other publications, and has in the past received grants from the Laura and John Arnold Foundation, the Helmsley Trust, and the John D. and Catherine T. MacArthur Foundation. All other authors declare that they have no competing interests.

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