Harshfield, Eric L.
Fauman, Eric B.
Stacey, David
Paul, Dirk S.
Ziemek, Daniel
Ong, Rachel M. Y.
Danesh, John
Butterworth, Adam S.
Rasheed, Asif
Sattar, Taniya
Zameer-ul-Asar,
Saleem, Imran
Hina, Zoubia
Ishtiaq, Unzila
Qamar, Nadeem
Mallick, Nadeem Hayat
Yaqub, Zia
Saghir, Tahir
Rizvi, Syed Nadeem Hasan
Memon, Anis
Ishaq, Mohammad
Rasheed, Syed Zahed
Memon, Fazal-ur-Rehman
Jalal, Anjum
Abbas, Shahid
Frossard, Philippe
Saleheen, Danish
Wood, Angela M.
Griffin, Julian L.
Koulman, Albert
Funding for this research was provided by:
British Heart Foundation (SP/09/002, RG/13/13/30194)
Medical Research Council (G0800270, MC_PC_13030, MC_PC_13030, MC_UP_A090_1006, MC_UP_A090_1006, G0800783, G0800783)
Medical Research Council (MR/L003120/1)
Wellcome Trust
Sixth Framework Programme (Bloodomics Integrated Project)
Pfizer
Novartis
Merck
NHS Blood and Transplant (NIHR BTRU-2014-10024)
National Institute for Health Research
British Heart Foundation (RG/18/13/33946)
Wellcome Trust (105602/Z/14/Z, 105602/Z/14/Z)
Article History
Received: 25 September 2020
Accepted: 4 August 2021
First Online: 10 September 2021
Declarations
:
: <i>PROMIS:</i> The institutional review board at the Center for Non-Communicable Diseases in Karachi, Pakistan, approved the study (IRB: 00007048, IORG0005843, FWAS00014490), and all participants gave informed consent, including for use of samples in genetic, biochemical, and other analyses.<i>INTERVAL:</i> Participants gave electronic informed consent. The National Research Ethics Service approved (11/EE/0538) this study.
: Not applicable.
: E.B.F. and D.Z. are employees and shareholders of Pfizer, Inc. J.D. has received research funding from the British Heart Foundation, the National Institute for Health Research Cambridge Comprehensive Biomedical Research Centre, the Bupa Foundation, diaDexus, the European Research Council, the European Union, the Evelyn Trust, the Fogarty International Centre, GlaxoSmithKline, Merck, the National Heart, Lung, and Blood Institute, the National Institute for Health Research [Senior Investigator Award], the National Institute of Neurological Disorders and Stroke, NHS Blood and Transplant, Novartis, Pfizer, the UK Medical Research Council, and the Wellcome Trust. J.L.G. has received funding from Agilent, Waters, GlaxoSmithKline, Medimmune, Unilever, AstraZeneca, the Medical Research Council, the Biotechnology and Biological Sciences Research Council, the National Institutes of Health, the British Heart Foundation, and the Wellcome Trust. D.Sa. has received funding from Pfizer, Regeneron Pharmaceuticals, Genentech, and Eli Lilly. All other authors declare no competing interests.