Joseph, Rebecca M. https://orcid.org/0000-0002-0147-0712
Jack, Ruth H. https://orcid.org/0000-0003-4009-020X
Morriss, Richard https://orcid.org/0000-0003-2910-4121
Knaggs, Roger David https://orcid.org/0000-0003-1646-8321
Butler, Debbie
Hollis, Chris https://orcid.org/0000-0003-1083-6744
Hippisley-Cox, Julia https://orcid.org/0000-0002-2479-7283
Coupland, Carol https://orcid.org/0000-0002-2327-3306
Funding for this research was provided by:
National Institute for Health Research (Nottingham Biomedical Research Centre, MindTech MedTech and in Vitro Fertilisation Collaboration, Applied Research Collaboration East Midlands)
Article History
Received: 12 October 2021
Accepted: 10 January 2022
First Online: 2 February 2022
Declarations
:
: The study used anonymised data provided under licence by the Clinical Practice Research Datalink (CPRD). The study protocol was approved by the Independent Scientific Advisory Committee which oversees access to CPRD data (protocol number 19_241).
: Not applicable
: All authors have completed the ICMJE uniform disclosure form at and declare support from the National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, NIHR School for Primary Care Research (RMJ, RHJ, JHC, CC), and NIHR MindTech MedTech Co-operative (RM, CH). JHC is a shareholder and former director of ClinRisk Ltd., outside of the submitted work. The other authors declare that they have no competing interests.