Wang, Minmin
Zhou, Hetong
Zhang, Xiaomei
Chen, Qianfeng
Tong, Qiqi
Han, Qiai
Zhao, Xudong
Wang, Dandan
Lai, Jianbo
He, Hongjian
Zhang, Shaomin
Hu, Shaohua
Funding for this research was provided by:
National Natural Science Foundation of China (52407261, 82201675, 52407261, 82201675)
National Key Research and Development Program of China (2023YFC2506200)
Research Project of Jinan Microecological Biomedicine Shandong Laboratory (No. JNL-2023001B)
Leading Talent of Scientific and Technological Innovation—“Ten Thousand Talents Program” of Zhejiang Province (2021R52016)
Innovation team for precision diagnosis and treatment of major brain diseases (2020R01001)
Chinese Medical Education Association (2022KTZ004)
Fundamental Research Funds for the Central Universities (226-2022-00193, 226-2022-00002, 2023ZFJH01-01, 2024ZFJH01-01)
Article History
Received: 11 December 2024
Accepted: 29 May 2025
First Online: 4 June 2025
Declarations
:
: All procedures were approved by the Clinical Research Ethics Committee of the First Affiliated Hospital, Zhejiang University School of Medicine (Approval number: IIT20230058 C-R1), ensuring compliance with the ethical standards and regulations of the Declaration of Helsinki on Human Research. This study was registered as a clinical trial with the Clinical Trial Registration (NCT05964777). All participants were fully informed of the study procedure and voluntarily signed a written informed consent form.
: Individual consent was obtained from all the participating patients.
: The authors declare no competing interests.