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Authors
Döding, Annika
Güllich, Alexander
Koch, Simon
de Miroschedji, Kyra
Schulze-Späte, Ulrike
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Funding
Funding for this research was provided by:
Novaxomx GmbH
German Federal Ministry of Education and Research (BMBF: 01EC1901B, Project 2)
Friedrich-Schiller-Universität Jena
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Article History
Received: 5 February 2025
Accepted: 1 September 2025
First Online: 21 October 2025
Declarations
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: Collection of human oral bone was approved by the Institutional Review Board of the University Hospital Jena (No. 2019–1440-Material) and carried out according to The Code of Ethics of the World Medical Association (Declaration of Helsinki). All patients had signed informed consent. All animal procedures and experimental protocols were approved by the local government and licensing institution (Thueringer Landesamt für Verbraucherschutz, TLV Abteilung 5, Bad Langensalza, Germany) and performed in strict compliance with the EU directives 86/609/EWG and 2007/526/EG guidelines for animal experiments. Following German animal welfare law, organ removal without pre-treatment of the animals is subject to an internal license: twz21-2017.
: All patients had signed informed consent and gave approval of publication of their data in written form.
: KdM is employed by Lysatpharma GmbH. Lysatpharma GmbH had no role in the study design, data analysis or interpretation of the results. All other authors report no conflict of interest.
