Huang, Xiao-Yong
Shi, Guo-Ming
Zheng, Zhi-Tao
Sun, Hui-Chuan
Liang, Fei
Ji, Yuan
Chen, Yi
Yang, Guo-Huan
Hu, Zhi-Qiang
Lu, Jia-Cheng
Meng, Xian-Long
Guo, Xiao-Jun
Zhang, Chao-Chen
Fan, Jia
Zhou, Jian
Funding for this research was provided by:
National Natural Science Foundation of China (82273234)
National Natural Science Foundation of China (81972232)
National Natural Science Foundation of China (81830102)
Shanghai Municipal Natural Science Foundation (21ZR1412200)
Shanghai Municipal Key Clinical Specialty Construction Project (shslczdzk02401)
Article History
Received: 24 February 2025
Accepted: 22 September 2025
First Online: 21 October 2025
Declarations
:
: The study protocol and all amendments were reviewed and approved by the Ethics Committee of each participating site, including the Ethics Committee of Zhongshan Hospital, Fudan University (approval number: B2020-038). The trial was conducted in accordance with the principles of the Declaration of Helsinki and the Good Clinical Practice (GCP) guidelines. Written informed consent was obtained from all participants prior to enrollment.
: Not applicable.
: The authors declare no competing interests.