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Concomitant use of direct oral anticoagulants and interacting antiarrhythmic drugs and the risk of stroke and bleeding among patients with non-valvular atrial fibrillation: a multinational cohort study

Crossref DOI link: https://doi.org/10.1186/s12916-025-04464-6

Published Online: 2025-10-28

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Meinert, Fabian Maximilian

Dimakos, Jenny

Cui, Ying

Filion, Kristian B.

Renoux, Christel

Douros, Antonios https://orcid.org/0000-0002-6005-4006
Funding

Funding for this research was provided by:

Charité - Universitätsmedizin Berlin
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Text and Data Mining valid from 2025-10-28

Version of Record valid from 2025-10-28
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Article History

Received: 20 May 2025

Accepted: 20 October 2025

First Online: 28 October 2025

Declarations

:

: The study protocol was approved by the independent Scientific Advisory Committee of the CPRD (protocol number: 23_002915), the ISQ, and the Research Ethics Board of the Jewish General Hospital Montreal, Canada. Informed consent was waived.

: Not applicable.

: The authors declare no competing interests.

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