Irizar, Patricia
Martin, Christopher A.
Woolf, Katherine
Nellums, Laura B.
Qureshi, Irtiza
Masood, Asad
Bryant, Luke
Goodwin, Laura
Pareek, Manish
,
Gray, Laura
Guyatt, Anna L
John, Catherine
McManus, I Chris
Abubakar, Ibrahim
Gupta, Amit
Aujayeb, Avinash
Gregary, Bindu
Reza, Rubina
Simpson, Sandra
Zingwe, Stephen
Abrams, Keither R
Tobin, Martin D
Wain, Louise
Carr, Sue
Dove, Edward
Khunti, Kamlesh
Ford, David
Free, Robert
Funding for this research was provided by:
Medical Research Council (MR/V027549/1)
National Institute for Health and Care Research
NIHR Leicester Biomedical Research Centre
NIHR Applied Research Collaboration East Midlands
UK Research and Innovation (MC_PC_19004)
Article History
Received: 20 March 2025
Accepted: 23 October 2025
First Online: 28 November 2025
Declarations
:
: The UK-REACH study was approved by the Health Research Authority (Brighton and Sussex Research Ethics Committee: 20/HRA/4718). All participants provided written, informed, consent.
: Not applicable.
: MP reports grants from Sanofi, grants and personal fees from Gilead Sciences, and personal fees from QIAGEN, outside the submitted work. The rest of the authors have no competing interest.