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Article History

Received: 28 May 2025

Accepted: 20 November 2025

First Online: 12 December 2025

Declarations

:

: The study was approved by Ile de France V ethics committee on 10th January 2018, ID RCB: 2017-A03028-45. Informed consent form was signed by every patient who has been included in the study (inform consent form available on request).

: Not applicable.

: Coraline Dubot: Payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events: GSK, AMGEN, MSD; Support for attending meetings and/or travel: Astra Zeneca, MSD, GSK, Eisai, Novartis, Lilly. Cyriac Blonz: receipt consulting/advisory fees (DAIICHI SANKYO, Lilly, MSD, Pfizer, Astra Zeneca). Jérôme Alexandre: Payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events: GSK, Astra Zeneca, MSD, Eisaï, Novartis; Support for attending meetings and/or travel: Astra Zeneca, MSD, Eisai. Frédéric Selle: Payment or honoraria for speakers’ bureaus, consulting or advisory role: Astra Zeneca, MSD, GSK-Tesaro, Eisai, Seagen, Abbvie. Sophie Frank: honoraria for lectures: Astra Zeneca; Support for attending meetings : Pharma And, Lilly, Pfizer. Florence Joly: Payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events: GSK, Astra Zeneca, MSD, Pharmand, Esai; Support for attending meetings and/or travel: GSK, ESAI, MSD. Patricia Pautier: Consulting fees: MSD, GSK; Payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events: MSD, GSK, PharmaMar; Support for attending meetings and/or travel: PharmaMar, MSD, GSK, Roche, Astra Zeneca. Elsa Kalbacher: Grants or contracts from any entity: GSK, MSD, Astrazeneca, Seagen, Tesaro; Consulting fees: GSK, MSD, Astrazeneca, Seagen, Tesaro; Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events: GSK, MSD, Astrazeneca, Seagen, Tesaro; Support for attending meetings and/or travel: GSK, MSD, Astrazeneca, Seagen, Tesaro, pharmamar, Esai, pharmaand. Thibaut De La Motte Rouge : Grants or contracts from any entity: MSD, Novartis, Pfizer; Consulting fees: Astra-Zeneca, pharmaand, Eisai, MSD, Natera, Pfizer, Roche, Sanofi, Seagen, GSK; Support for attending meetings and/or travel: Astra-Zeneca, MSD, Pfizer, Roche, GSK. Jean-Emmanuel Kurtz : Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events: GSK, Johnson&Johnson; Support for attending meetings and/or travel: GSK, PharmaMar, MSD, AstraZeneca; Participation on a Data Safety Monitoring Board or Advisory Board: GSK Dominique Berton Rigaud, Tiphaine Renaud, Magali Provansal, Paule Augereau, Cédric Nadeau, Hubert Orfeuvre, Brunhilde Hanvic, Isabelle Ray-Coquard, Brice Fresneau, François Gernier, Djihanne Ahmed-Lecheheb, Benedicte Clarisse, Jean-Michel Grellard, Justine Lequesne, François Christy : none