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Authors
Long, Xingru
An, Shuxian
Nian, Xuanbingning
Xu, Dongsheng
Wei, Weijun
Lan, Xiaoli
Dong, Liang
Jiang, Dawei
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (82030052)
National Natural Science Foundation of China (22277031)
Innovative Drug Research and Development-National Science and Technology Major Project (2025ZD1803403)
Hubei Science and Technology Innovation Talent Program (2023DJC162)
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Article History
Received: 18 August 2025
Accepted: 15 December 2025
First Online: 31 December 2025
Declarations
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: The animal study protocol was approved by the Institutional Animal Care and Use Committee at Tongji Medical College, Huazhong University of Science and Technology (Approval Number: 4494). The human study was approved by the Ethics Committee of Renji Hospital, School of Medicine, Shanghai Jiao Tong University (Approval Number: LY2024-307-A) and registered in ClinicalTrials.gov (NCT06851663). Written informed consent forms were obtained from all the included patients.
: All patients gave written informed consent. All authors have read and approved of its submission to this journal.
: The authors declare no competing interests.
