Zhu, Nanbo
Eriksdotter, Maria
Shahim, Bahira
Johnell, Kristina
Garcia-Ptacek, Sara
Carrero, Juan-Jesus
Xu, Hong
Funding for this research was provided by:
ALF agreement between Region Stockholm and Karolinska Institutet
Vetenskapsrådet (2024-03599)
Vetenskapsrådet (2022-01472)
Vetenskapsrådet (2022-01425)
Vetenskapsrådet (2023-01807)
Vetenskapsrådet (2022-01428)
Hjärnfonden
Karolinska Institutet
Stockholms Läns Landsting (FoUI-988371)
Hjärt-Lungfonden (20220524)
Hjärt-Lungfonden (20230371)
Svenska Sällskapet för Medicinsk Forskning (SG-23-0142-B)
Svenska Läkaresällskapet (987010)
Emil och Wera Cornells Stiftelse
Alzheimerfonden
Swedish Dementia Research Foundation
New Innovative Roads Call - a private initiative from the Leif Lundblad family and others
Foundation for the National Institutes of Health (NIH R01DK115534)
Njurfonden
Martin Rinds Stiftelse
Stiftelsen Stig och Gunborg Westman
Center for Innovative Medicine (FoUI-963369; FoUI-1002840)
Åke Wiberg Stiftelse (M22-0170; M24-0221)
Petrus och Augusta Hedlunds Stiftelse (M-2024-2526)
Magnus Bergvalls Stiftelse (2024-1370)
Ulla Hamberg Angeby and Lennart Angeby Foundation (2022-02882)
Karolinska Institute
Article History
Received: 14 August 2025
Accepted: 23 February 2026
First Online: 28 February 2026
Declarations
:
: This study was approved by the regional ethical review board in Stockholm and the Swedish National Board of Health and Welfare (Dnr: 2017/793–31). Individual informed consent was not required as the study was register-based.
: Not applicable.
: ME has served as a consultant for BioArctic AB, Roche, Eli Lilly, Biogen/Eisai, and Novo Nordisk and has given lectures in symposia sponsored by Roche. JJ-C reports funding to Karolinska Institutet by AstraZeneca, Astellas, Vifor Pharma, Novo Nordisk, and MSD, all unrelated to this study; personal honoraria for lectures by Fresenius Kabi; and being a member of advisory boards for Fresenius Kabi and Boehringer Ingelheim. All other authors have nothing to disclose.