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Authors
Zhao, Xudong
Zhou, Hetong
Zhang, Xiaomei
Tang, Ruoyu
Gan, Yimei
Zhuang, Tongjie
Zhu, Yiyi
Qin, Zeyu
Chen, Yiqing
Fu, Yaoyang
Zhang, Danhua
Xu, Le
Wang, Shiliang
Shen, Zhongxia
Hu, Shaohua
Wang, Minmin
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Funding
Funding for this research was provided by:
Zhejiang Province Medical and Health Science and Technology Plan Project (2025KY1557)
Public Welfare Applied Research Project on Population Health (Medical & Health Focus) of Huzhou Municipal Science and Technology Bureau (2024GZ86)
Fundamental Research Funds for the Central Universities (226-2022-00193, 226-2022-00002, 2023ZFJH01-01, 2024ZFJH01-01)
Zhejiang Provincial Basic Public Research Program (LTGY23H090013)
Zhejiang Provincial Key Research and Development Program (2025C01137)
National Natural Science Foundation of China (52407261, 82201675)
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Article History
Received: 30 July 2025
Accepted: 27 February 2026
First Online: 7 March 2026
Declarations
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: All procedures were approved by the Clinical Research Ethics Committee of the First Affiliated Hospital, Zhejiang University School of Medicine (Reference ID: IIT20220081C-R1), ensuring compliance with the ethical standards and regulations of the Declaration of Helsinki on Human Research. This study was registered as a clinical trial with the Clinical Trial Registration (Registration number: NCT05929183). All participants were fully informed of the study procedure and voluntarily signed a written informed consent form.
: Individual consent was obtained from all the participating patients.
: The authors declare no competing interests.
