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Authors
Dothard, Marisol I.
Caboni, Mariaelena
Norment, Daniel
Sigmund, Nolan
Allard, Sarah M.
Gilbert, Jack A.
Gavrish, Ekaterina
Al-Ghalith, Gabriel
Der-Avakian, Andre
Strandwitz, Philip
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Funding
Funding for this research was provided by:
National Institute of Health Small Business Innovation Research (R44DK120181)
National Science Foundation Graduate Research Fellowship Program (DGE-2038238)
Translational Research Institute for Space Health - Space Health Ingress Program (NNX16AO69A)
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Article History
Received: 21 August 2025
Accepted: 6 March 2026
First Online: 10 March 2026
Declarations
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: The Advarra Institutional Review Board approved the collection of feces from human subjects at Holobiome (Pro00069198). Informed written consent was obtained from all participants.Procedures involving animals were approved by the UC San Diego Institutional Animal Care and Use Committee (see Additional File 7: Completed ARRIVE guidelines 2.0 checklist).
: Not applicable.
: PS: Founder, employee, and shareholder of Holobiome. JG: Scientific Advisory Board member and shareholder of Holobiome. MC, EG, GA: Employees and shareholders of Holobiome; DN: Shareholder of Holobiome. MD, NS, SA, AD: these authors declare that they have no competing interests. PS, MC, and EG are named as inventors on patent applications related to this work, including a published international application (WO2017160711A1) and a pending provisional patent application.
