Wang, Chunming
Cai, Lei
Yang, Yongguang
Wang, Weidong
Zhao, Kunli
Xie, Wenchuan
Zhou, Qiaoxia
Zhang, Qifan
Zhang, Cheng
Deng, Meihai
Bao, Shiyun
Bi, Jiangang
Chen, Xuefang
Xie, Haorong
Fu, Shunjun
He, Guolin
Cheng, Yuan
Zhong, Kaihang
Wen, Yaohong
Xu, Yuyan
Duan, Feidie
Liu, Fang
Shi, Yezhen
Yao, Jiaqi
Xu, Jiayue
Zhao, Jing
Zhang, Yuzi
Wang, Guoqiang
Han, Yusheng
Yang, Tian
Cai, Shangli
He, Junming
Pan, Mingxin https://orcid.org/0000-0002-9133-3323
Funding for this research was provided by:
Basic and Applied Basic Research Foundation of Guangdong Province (2023A1515220159)
Basic and Applied Basic Research Foundation of Guangdong Province (2021B1515230011)
The Key Research and Development Plan of Guangzhou (2024B03J1381)
National Natural Science Foundation of China (82372813, 82273074, 82425049)
National Natural Science Foundation of China (82072627)
Clinical high-tech project in Guangzhou region (2024P-GX20)
Article History
Received: 7 January 2026
Accepted: 24 June 2026
First Online: 6 July 2026
Declarations
:
: This study was approved by the Ethics Committee of Zhujiang Hospital of Southern Medical University (2021-KY-013-01). Conducted in adherence to the principles of the Declaration of Helsinki, all participants provided written informed consent.
: Not applicable.
: K.Z.1, W.X., Q.Z.2, F.L., Y.S., J.Y., J.X., J.Z., Y.Z., G.W., S.C., F.D., and Y.H. declare employment at Burning Rock Biotech. All other authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. All statistical analyses presented in the manuscript were conducted independently by the academic authors, who had full access to the primary raw data and take responsibility for the integrity and accuracy of the results.