Camargo-Romera, Paula
Castresana‑Aguirre, Miguel
Danielsson, Oscar
Dar, Huma
Östman, Arne
Czene, Kamila
Lindström, Linda S.
Tobin, Nicholas P.
Funding for this research was provided by:
Karolinska Institute
Article History
Received: 13 January 2026
Accepted: 21 July 2026
First Online: 5 August 2026
Declarations
Ethics approval and consent to participate: The STO trials were approved by the Karolinska Institutet Regional Ethics Committee, with the Stockholm Regional Cancer Center serving as the trial centre. Written informed consent was obtained from all participants before randomisation. The STO trial was initiated in 1976, before the practice of trial registration in Sweden; therefore, no trial registration number is available.
Consent for publication: Not applicable.
Competing interests: The authors declare no competing interests.