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Article History

Received: 23 October 2017

Accepted: 15 March 2018

First Online: 27 March 2018

Ethics approval and consent to participate

: All studies were approved by the Institutional Animal Care and Use Committee, Boston Scientific Corporation, with full approval and consent of all Class A research animals in accordance with the policies and guidelines of our institution, which is an AAALAC International accredited facility. All studies complied with animal use regulations as set forth in the United States Department of Agriculture Animal Welfare Act, 9, CFR, and adhered to the principles outlined in the "Guide for the Care and Use of Laboratory Animals," from the National Research Council.

: Not applicable

: Both Lynne Swanson and Barbara Huibregtse are employees of Boston Scientific Corporation, who funded all studies reviewed within this manuscript.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.