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Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrPCWD deposition in orally infected white-tailed deer

Crossref DOI link: https://doi.org/10.1186/s12917-019-1794-z

Published Online: 2019-02-04

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Otero, Alicia

Duque Velásquez, Camilo

Johnson, Chad

Herbst, Allen

Bolea, Rosa

Badiola, Juan José

Aiken, Judd

McKenzie, Debbie http://orcid.org/0000-0002-9291-6977
Funding

Funding for this research was provided by:

Department of Defense National Prion Research Program (DAMD17-03-1-0294)

Alberta Prion Research Institute (PEX13004)

Genome Canada (GC-LSARP)
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Article History

Received: 1 October 2018

Accepted: 22 January 2019

First Online: 4 February 2019

Ethics approval and consent to participate

: Experiments involving deer sampled in the present study were conducted in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. The protocol was approved by the School of Veterinary Medicine Animal Care and Use Committee at the University of Wisconsin (Permit Number: V910). Details of CWD oral challenge have been previously published [CitationRef removed].

: Not Applicable.

: The authors declare that they have no competing interests.

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