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Authors
Monteiro, Beatriz P.
Lambert, Cedric
Bianchi, Elena
Genevois, Jean Pierre
Soldani, Giulio
Troncy, Eric http://orcid.org/0000-0003-0209-5261
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Funding
Funding for this research was provided by:
Merial Animal Health Inc. (Operating grant)
Natural Sciences and Engineering Research Council of Canada (#327158–2008, #441651–2013, #RDCPJ 418399–2011, #RDCPJ 491953-2016)
Canada Foundation for Innovation (#9483, #24601)
Government of Canada (Vanier Graduate Scholarship)
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Article History
Received: 24 August 2018
Accepted: 13 June 2019
First Online: 25 June 2019
Ethics approval and consent to participate
: The study was approved by the local Institutional Animal Care and Use Committee of the VetAgro-Sup of Lyon (protocol JB/EG 14/23/X). It was performed at the <i>Centre hospitalier universitaire vétérinaire</i> (CHUV) – Small Animal Clinic and Medical Biology Laboratory, Lyon, France in collaboration with the University of Pisa, Italy. This study is reported according to the CONSORT () for reporting a randomized trial and ARRIVE guidelines () for reporting animal experiments.Client-owned dogs of any sex or breed, older than 1 year of age, weighting from 10 to 60 kg, and presenting clinical and radiographic evidence of OA were included in a randomized prospective controlled double-blinded clinical trial after obtaining owner’s written consent.At the end of the study, the dogs either returned in the institutional research colony (Group A, <i>n</i> = 5) or stayed at home (Groups B and C, <i>n</i> = 20).
: Not applicable.
: The authors declare that this study was sponsored in part by Merial Animal Health Inc., Lyon, France. The authors declare that they have no competing interests.
