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Article History

Received: 29 August 2025

Accepted: 10 October 2025

First Online: 19 December 2025

Declarations

:

: All experimental protocols in this study were approved by the Animal Use Ethics Committee of the Federal University of Rio Grande do Sul (UFRGS) (Protocol No. 33329). All methods comply with the ARRIVE guidelines for reporting animal experiments. All reported methods were conducted in accordance with the relevant guidelines and regulations of the National Council for the Control of Animal Experimentation (CONCEA).

: Not applicable.

: The authors declare no competing interests.