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Computational modelling of energy balance in individuals with Metabolic Syndrome

Crossref DOI link: https://doi.org/10.1186/s12918-019-0705-z

Published Online: 2019-02-26

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Rozendaal, Yvonne J. W. https://orcid.org/0000-0003-1812-7694
Wang, Yanan

Hilbers, Peter A. J.

van Riel, Natal A. W.
Funding

Funding for this research was provided by:

FP7 Health (305707)

ZonMw (91617027)
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Text and Data Mining valid from 2019-02-26
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Article History

Received: 2 July 2018

Accepted: 14 February 2019

First Online: 26 February 2019

Ethics approval and consent to participate

: This animal study was performed in accordance with the regulations of Animal welfare and rights in the Netherlands (The Animals Act 2011). The Animal Ethics Committee of the Leiden University Medical Center, Leiden, The Netherlands approved all animal experiments and protocols. After 12-weeks dietary intervention, mice were euthanized by CO<sub>2</sub> suffocation and blood was collected via cardiac puncture. Unconscious mice were perfused with ice-cold saline via the cardiac perfusion, and various organs were isolated for further analysis.

: Not applicable.

: The authors declare that they have no competing interests.

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