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Article History

First Online: 13 February 2018

Ethics approval and consent to participate

: All methods were performed in accordance with relevant guidelines and regulations.All experimental protocols were approved by IRB on Biomedical Science Research/IRB-BM, Academia Sinica (AS-IRB03–105025), issued to Taiwan Biosignature Project for Breast Cancer: Investigate the Presence of Circulating DNA with Specific Mutations Identified by Whole Exome Sequencing of Early-onset Breast Cancer.

: Written informed consents for publication of clinical details were obtained from patients and from healthy individuals as well. No images are involved in this report.

: The authors declare that they have no competing interests.

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