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Article History

Received: 6 November 2025

Accepted: 11 February 2026

First Online: 21 February 2026

Declarations

:

: This study was conducted in accordance with the provisions of the Declaration of Helsinki. Ethical approval has been obtained from Scientific Research and Clinical Trial Ethics Committee of the First Affiliated Hospital of Zhengzhou University, with the approval number: 2022-KY-0269-003 and approval date: 2022-11. All patients provided written informed consent for the use of their clinical samples in transcriptome data sequencing experiments, ensuring that the research process complies with ethical standards and fully respects the rights, interests and wishes of the patients.

: Not applicable.

: The authors declare no competing interests.