Nogueira, Glenda Menezes https://orcid.org/0000-0001-6110-7766
Gonçalves, Luca Gabriel Marques https://orcid.org/0009-0009-2839-8253
Pereira-Ribeiro, Thaís Lohana https://orcid.org/0000-0002-1471-4472
Santos, Larissa Silva https://orcid.org/0009-0009-4125-8239
Magalhães-Gama, Fábio https://orcid.org/0000-0003-1373-0953
Araújo, Nilberto Dias https://orcid.org/0000-0002-2107-3677
Malheiro, Adriana https://orcid.org/0000-0002-1107-8079
Tarragô, Andréa Monteiro https://orcid.org/0000-0003-3125-580X
Alves-Hanna, Fabíola Silva https://orcid.org/0000-0002-1582-2969
Costa, Allyson Guimarães https://orcid.org/0000-0002-7312-6822
Funding for this research was provided by:
Fundação de Amparo à Pesquisa do Estado do Amazonas (POSGRAD Program - #002/2025 and #015/2026)
Fundação de Amparo à Pesquisa do Estado do Amazonas (PRÓ-ESTADO Program - #002/2008, #007/2018, #005/2019)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (INCT-Sangue – Process #405918/2022-4)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (PDPG-CONSOLIDACAO-3-4 Program – Process #88887.707248/2022-00)
Article History
Received: 23 January 2026
Accepted: 8 April 2026
First Online: 14 April 2026
Declaration of interest
: The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s. Due to ethical restrictions regarding patient privacy, data are available upon request. Data are available upon request from the Ethics Committee of HEMOAM (CEP-HEMOAM), cep@hemoam.am.gov.br, for researchers who meet the criteria for access to confidential data. Additional requests for the data may be sent to the corresponding author or coauthors Allyson G. Costa (allyson.gui.costa@gmail.com) and Fabíola S. Alves-Hanna (fabiolasiilva@hotmail.com).
: All study protocols and informed consent procedures were approved by the Research Ethics Committee of HEMOAM (CEP/HEMOAM; approval number 3,335,123/2019). All patients were treated in accordance with the guidelines and recommendations of the Brazilian Ministry of Health.
: The authors declare no competing interests.