Updates are available Correction dated 2018-04-24

Article History

Received: 1 August 2017

Accepted: 10 January 2018

First Online: 24 January 2018

Change Date: 24 April 2018

Change Type: Correction

Change Details: In the original publication [1] is an incorrect sentence in the abstract under Conclusions.

Ethics approval and consent to participate

: Not applicable

: Not applicable

: Fabiano Di Marco has received honoraria for lectures at national and international meetings from Almirall, AstraZeneca, Boehringer Ingelheim, Chiesi Farmaceutici, Dompe, Guidotti/Malesci, GlaxoSmithKline, Menarini, Novartis, and Zambon. He has served as consultant for AstraZeneca, Chiesi Farmaceutici, Novartis, and Zambon. He has received financial support for research from Novartis, and Boehringer Ingelheim.Pierachille Santus participated as a lecturer, speaker, and advisor in scientific meetings and courses under the sponsorship of AstraZeneca, Boehringer Ingelheim, Chiesi Farmaceutici, GlaxoSmithKline, Menarini, Malesci, Guidotti, Mundipharma, Novartis, Zambon. He has received financial support for research from Chiesi, Boehringer Ingelheim and Almirall.Denis O’Donnell has received research funding via Queen’s University from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline; and has served on speakers bureaus, consultation panels and advisory boards for Almirall, AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Novartis and Pfizer.Kai-Michael Beeh declares no personal payments were received from any pharmaceutical entity in the past 5 years. The institution he represents has received compensation: 1) for services on advisory boards or consulting for Ablynx, Almirall, AstraZeneca, Berlin Chemie, Boehringer, Chiesi, Cytos, Mundipharma, Novartis, Pohl Boskamp, Zentiva; 2) for speaker activities in scientific meetings supported by Almirall, AstraZeneca, Berlin Chemie, Boehringer, Cytos, ERT, GSK, Novartis, Pfizer, Pohl Boskamp, Takeda; 3) for design and performance of clinical trials from Almirall, Altana/Nycomed, AstraZeneca, Boehringer, Cytos, GSK, Infinity, Medapharma, MSD, Mundipharma, Novartis, Parexel, Pearl Therapeutics, Pfizer, Revotar, Teva, Sterna, and Zentiva.Francesco Blasi has received research grants from Bayer, Chiesi, Zambon, and Pfizer, congress lecture fees from AstraZeneca, Guidotti, Menarini, GSK, Chiesi, Pfizer, and Novartis, and consultancy fees from AstraZeneca, Menarini,Novartis, GSK, Zambon,Teva and Pfizer.Stefano Centanni has received financial support for research from Novartis and Pfizer. He has served as a consultant for AstraZeneca, Novartis, Chiesi Farmaceutici, Boehringer Ingelheim, GlaxoSmithKline, Mundipharma, and Almirall.Giovanni Sotgiu, Simone Dore, Maria Adelaide Roggi, and Lisa Giuliani declare no conflicts of interest.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.