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Article History

Received: 22 February 2018

Accepted: 8 June 2018

First Online: 15 June 2018

Ethics approval and consent to participate

: The study was approved by the Ethics Committee of the Balearic Islands (CI-IB number 849/07) and all participants signed their informed consent.

: Not applicable.

: Dr. Agusti reports, outside the submitted work, grants and personal fees from Astra-Zeneca, GSK and Menarini, grants from MSD and personal fees from Novartis, TEVA and Chiesi. Dr. Cosio reports personal fees from AstraZeneca, Rovi and Esteve, grants from Boehringer and grants and personal fees from Novartis, Chiesi and Menarini, all of them outside the submitted work. All the other authors have no conflict of interest to declare.

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