Received: 5 October 2018
Accepted: 2 January 2019
First Online: 15 January 2019
Ethics approval and consent to participate
: Experiments in mice were approved by the local committee for animal welfare (CMMI).For the human study, the protocol has been approved by the Erasme hospital Ethics Committee (ref. P2016/427). Written informed consent for participation in the study was obtained from all the patients.
: Not applicable.
: B.B. received grants, consultancies and lecture fees from La Roche-Hoffmann and Boehringer Ingelheim. Other authors declare that they have no competing interests.
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