Document is current

Article History

Received: 16 February 2019

Accepted: 5 August 2019

First Online: 22 August 2019

Ethics approval and consent to participate

: Study protocol has been approved by the Ethics Committee of Versailles Saint Quentin University, authorization number 04–479, for protection of human beings involved in biomedical research. The study has also been approved by CCTIRS (Comité Consultatif sur le Traitement de l’Information en matière de Recherche dans le domaine de la Santé), on the 6th January, 2005 (04–479). All patients provided written consent.

: All patients provided written consent. All authors provided consent to publication.

: MZ reports grants and personal fees from Boehringer Ingelheim, personal fees from Novartis, personal fees from Chiesi, and personal fees from GSK outside the submitted work.PRB reports personal fees from Aptalis, personal fees from Astra-Zeneca, grants and personal fees from Boehringer Ingelheim, personal fees from Chiesi, personal fees from GSK, personal fees from Novartis, personal fees from Pfizer, personal fees from Vertex, personal fees from Zambon, outside the submitted work.ICF reports grants and personal fees from Boehringer Ingelheim, grants and personal fees from Novartis, outside the submitted work.GBR reports grants and personal fees from Boehringer Ingelheim, grants and personal fees from Novartis, personal fees and non-financial support from Chiesi, outside the submitted work.PNM reports grants and personal fees from Boehringer Ingelheim, grants and personal fees from NOVARTIS, personal fees and non-financial support from Chiesi, outside the submitted work.PS reports grants and personal fees from Boehringer Ingelheim outside the submitted work.GD reports personal fees from Novartis, personal fees from Astra Zeneca, personal fees from BTG/PneumRx, personal fees from Chiesi, personal fees from Boehringer Ingelheim, outside the submitted work.TP reports personal fees from Boehringer Ingelheim, personal fees from Novartis, personal fees from GSK, personal fees from Chiesi, personal fees from Pierre Fabre, outside the submitted work.OLR reports grants and personal fees personal fees and non-financial support from Astra Zeneca, Boehringer Ingelheim, Chiesi, Lilly and Novartis; non-financial support from Glaxo Smith Kline, MundiPharma, Pfizer, Teva, Santelys Association, Vertex and Vitalaire, all outside the submitted work.GJ reports personal fees from Boehringer Ingelheim, personal fees from GSK, personal fees from Novartis, personal fees from Menarini, personal fees from Astra Zeneca, personal fees from Chiesi, outside the submitted work.PC reports personal fees from Boehringer Ingelheim, personal fees from GSK, personal fees from ALK, personal fees from Novartis, personal fees from Teva, personal fees from Astra Zeneca, personal fees from Chiesi, personal fees from Sanofi, personal fees and non-financial support from SNCF, outside the submitted work.JLP reports grants from iBPCO association, during the conduct of the study.DC has nothing to disclose.NRreports grants and personal fees from Boehringe rIngelheim, grants and personal fees from Novartis, personal fees from Teva, personal fees from GSK, personal fees from AstraZeneca, personal fees from Chiesi, personal fees from Mundipharma, personal fees from Cipla, grants and personal fees from Pfizer, personal fees from Sanofi, personal fees from Sandoz, personal fees from 3 M, personal fees from Zambon, outside the submitted work.