Criner, Rachel N. http://orcid.org/0000-0003-4207-641X
Hatt, Charles R.
Galbán, Craig J.
Kazerooni, Ella A.
Lynch, David A.
McCormack, Meredith C.
Casaburi, Richard
MacIntyre, Neil R.
Make, Barry J.
Martinez, Fernando J.
Labaki, Wassim W.
Curtis, Jeffrey L.
Han, Mei Lan K.
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (U01 HL089897, U01 HL089856, K24 HL138188)
AstraZeneca
Boehringer Ingelheim
GlaxoSmithKline
U.S. Department of Veterans Affairs (I01 CX000911)
Novartis (None)
Sunovion (None)
Article History
Received: 21 September 2019
Accepted: 8 November 2019
First Online: 2 December 2019
Ethics approval and consent to participate
: This research letter presents an analysis of the COPDGene study registered on Clinicaltrials.gov (NCT00608764). The protocol was reviewed and approved by the Institutional Review Boards for each participating center (National Jewish Health, HS-1883a; Brigham and Women’s Hospital, 2007-P-000554/2; Baylor College of Medicine, H-22209; Michael E. DeBakey VAMC, H<sup>− 22202</sup>; Columbia University Medical Center, IRB-AAAC9324; Duke University Medical Center, Pro00004464; Johns Hopkins University, NA_00011524; Los Angeles Biomedical Research Institute, 12756–01; Morehouse School of Medicine, 07–1029; Temple University, 11369; University of Alabama at Birmingham, FO70712014; University of California, San Diego, 070876; University of Iowa, 200710717; Ann Arbor VA, PCC 2008–110732; University of Minnesota, 0801 M24949; University of Pittsburgh, RO07120059; University of Texas Health Sciences Center at San Antonio, HSC20070644H; Health Partners Research Foundation, 07–127; University of Michigan, HUM00014973; Minneapolis VA Medical Center, 4128-A; Fallon Clinic, 1143).
: Not applicable.
: RNC, EAK, NM, RC, WWL – none.CRH – An employee of and has stock options in Imbio LLC, which has licensed the PRM technology for use as FDA-approved commercial software.DAL - Reports grants from NHLBI and has a pending patent entitled Systems and Methods for Classifying Severity of COPD.CJG – Is co-inventor of PRM, which is licensed to Imbio by the University of Michigan.MM – Reports other support from UpToDate.BM – Reports funding from the NHLBI for the COPDGene study; grants and medical advisory boards from Boehringer Ingelheim, GlaxoSmithKline, AstraZeneca, and Sunovian; personal fees for DSMB from Spiration and Shire/Baxalta; CME personal fees from WebMD, National Jewish.Health, American College of Chest Physicians, Projects in Knowledge, Hybrid Communications, SPIRE Learning, Ultimate Medical Academy, Catamount Medical, Eastern Pulmonary Society, Catamount Medical Communications Medscape, Eastern VA Medical Center, Academy Continued Healthcare Learning, and Mt. Sinai Medical Center; royalties from Up-To-Date; medical advisory boards from Novartis, Phillips, Third Pole, Science 24/7, and Vernoa; and grants from Pearl.FJM - Receives personal fees and non-financial support from American College of Chest Physicians, AstraZeneca, Boehringer Ingelheim, ConCert, Genentech, GlaxoSmithKline, Inova Fairfax Health System, Miller Communications, National Association for Continuing Education, Novartis, Pearl Pharmaceuticals, PeerView Communications, Prime Communications Puerto Rican Respiratory Society, Chiesi, Sunovion, Theravance, Physicians Education Resource, Canadian Respiratory Network, Teva, and Dartmouth. Receives non-financial support from ProterrixBio, Gilead, Nitto, Potomac, University of Alabama Birmingham, and Zambon. Receives personal fees from Columbia University, Integritas, MD Magazine, Methodist Hospital Brooklyn, New York University, UpToDate, WebMD/MedScape, Western Connecticut Health Network, Patara/Respivant, PlatformIQ, American Thoracic Society, Rockpointe, Rare Disease Healthcare Communications, and France Foundation. He receives grants from the NIH. He also receives other support from Afferent/Merck, Biogen, Veracyte, Prometic, Bayer, Bridge Biotherapeutics, and ProMedior.JLC - Reports grants from NIH/NHLBI, NIH/NIAID, the Department of Veterans Affairs, and the Department of Defense.MKH - Reports grants from NIH, personal fees from BI, GSK, AZ, and Mylan. She also receives other support from Novartis and Sunovion.