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Authors
Cipolla, David
Zhang, Jimin
Korkmaz, Brice
Chalmers, James D.
Basso, Jessica
Lasala, Daniel
Fernandez, Carlos
Teper, Ariel
Mange, Kevin C.
Perkins, Walter R.
Sullivan, Eugene J.
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Clinical Trials BETA
Clinical trials referenced in this document:
nct03218917 at ClinicalTrials.govDocuments that mention this clinical trial
T3 Immunomodulatory effects of the Dipeptidyl peptidase-1 inhibitor brensocatib in patients with bronchiectasis: data from the phase 2 WILLOW trial
https://doi.org/10.1136/thorax-2024-btsabstracts.3
P112 Efficacy and safety of Dipeptidyl Peptidase-1 (DPP-1) inhibition in long-term macrolide users with bronchiectasis: a post-hoc analysis of the WILLOW trial
https://doi.org/10.1136/thorax-2023-btsabstracts.264
P111 Dipeptidyl peptidase-1 inhibition in bronchiectasis with eosinophilic endotype in the WILLOW trial
https://doi.org/10.1136/thorax-2023-btsabstracts.263
Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial
https://doi.org/10.1186/s12931-023-02444-z
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Article History
Received: 28 February 2023
Accepted: 7 May 2023
First Online: 17 May 2023
Declarations
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: The WILLOW trial was performed in accordance with the ethical principles of the Declaration of Helsinki, International Conference on Harmonisation Good Clinical Practice guidelines, and applicable regulatory requirements. Approvals from independent ethics committees were obtained. Informed consent was obtained from all subjects involved in the study.
: Not applicable.
: DC, JS, DL, CF, AT, KGM, JZ, WP and EJS are employees of Insmed Incorporated, Bridgewater, New Jersey. JDC has received grants and personal fees from AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Zambon, and Insmed Incorporated; a grant from Gilead; and personal fees from Novartis and Chiesi. BK has received personal fees from Insmed Incorporated.
