Sharma, Rinku
Kelly, Rachel S.
Mendez, Kevin
Chen, Qingwen
Hecker, Julian
Begum, Sofina
Clish, Clary
Celedón, Juan C.
Tantisira, Kelan G.
Weiss, Scott T.
Lasky-Su, Jessica
McGeachie, Michael J.
Funding for this research was provided by:
National Heart, Lung, and Blood Institute
Article History
Received: 31 July 2025
Accepted: 10 December 2025
First Online: 7 January 2026
Declarations
:
: Written parental and participating child consent was obtained. This study was conducted in accordance with the Declaration of Helsinki and was approved by the Partners Human Research Committee at Brigham and Women’s Hospital (Boston, USA); Protocol#: 2000-P-001130/55, and the Hospital Nacional de Niños (San José, Costa Rica).
: Not applicable.
: STW has received royalty payments from UpToDate. He is also on the Board of Histolix a digital pathology company. Dr. Celedón received research materials (inhaled steroids) from Merck in order to provide medications free of cost to participants in an NIH-funded study, unrelated to the current work. The other authors have no relevant competing interests to disclose.