Xu, Rui
Li, Liangyuan
Shen, Yongchun
Tang, Xiaoju
Zhu, Hui
Wang, Kaige
Xu, Hong
Xie, Liheng
Su, Chenhui
Jiang, Yuying
Liu, Dan
Luo, Fengming
Funding for this research was provided by:
Noncommunicable Chronic Diseases-National Science and Technology Major Project (2024ZD0522604 / 2024ZD0522600 to S Li)
Noncommunicable Chronic Diseases-National Science and Technology Major Project (2024ZD0522604 / 2024ZD0522600 to S Li)
National Natural Science Foundation of China (82173182)
Science and Technology Program of Sichuan (2023NSFSC1939)
Chengdu Science and Technology Project (2023-YF09-00039-SN)
Article History
Received: 7 September 2025
Accepted: 3 January 2026
First Online: 13 January 2026
Declarations
:
: This animal study was approved by the Ethical Committee of WestPoint Innovation Center (Ethical Approval number: IAC21110101, IAC22041801), and treatment of the animals was in accordance with the Animal Welfare Act of 1966 and all efforts were made to minimize animal suffering and to use the minimum number of animals necessary to produce reliable scientific data. This clinical study was approved by Ethical Committee of West China Hospital of Sichuan University (Ethical Approval number: 2021-426) and in accordance with the Declaration of Helsinki (1996), Good Clinical Practice guidelines, and local requirements. The trial was registered on the Chinese Clinical Trial Registry (chiCTR.gov, No. ChiCTR2100047843, 27 June, 2021). The date of enrolment of the first research participant was 15 September, 2021. Patients or their representatives provided signed informed consent forms before participation in the study.
: Not applicable.
: The authors declare no competing interests.